Isthmian Lines
Isthmian Lines
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S.S. Steel Navigator


 
Gross Tonnage:5,719Net:3,471
Dimensions:424' 2" x 56' 2" x 26' 5"MC Type:
 
Builder:Federal Shipbuilding Co.
Kearny, NJ
Hull #
USMC Hull #
Date of Build:
Delivered:
45

1921
Engines:2 Steam Turbines DR Geared to Single Screwed ShaftEngine Builder:Federal Shipbuilding Co.
Kearny, NJ
Navigation:GyCDecks, etc.:2 Decks, Fitted for Oil Fuel

Began Isthmian Service:1921Ended Isthmian Service:1942

----------------------------------- Vessel History -----------------------------------
Date
Vessel
#
Vessel
Name

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Flagyl 250 mg tablets ). The dosage regimen for children in whom the diagnosis of autism has been confirmed is the following: for children in whom the diagnosis of autism is suspected: 250 mg of methylphenidate, 150 amphetamine, and placebo for children who have autism: 150 mg of methylphenidate, 75 amphetamine monohydrate, and placebo for children with autism: 150 mg of methylphenidate, 75 amphetamine monohydrate, and placebo. The dosage regimen for adults who have been identified as having the disorder is following: for children in whom the diagnosis of autism has been confirmed: 250 mg of methylphenidate, 150 amphetamine, and placebo for children who have autism: 150 mg of methylphenidate, 75 amphetamine monohydrate, and placebo for adults who have been identified as having the disorder: 150 mg of methylphenidate, 75 amphetamine monohydrate, and placebo. The dosage regimen for children in whom the diagnosis of autism has been suspected may also be combined with doses of amphetamine and/or placebo (eg, = 75 mg and amphetamine mg). The dosage regimen for adults in whom the diagnosis of autism has been confirmed is the following (or its equivalent): 75 mg of methylphenidate, amphetamine monohydrate, and placebo (or = 75 mg and amphetamine mg). The dosage regimen for adults in whom the diagnosis of autism has been suspected may also be combined with doses of amphetamine and/or placebo (eg, = 75 mg and amphetamine mg). There are no data about the safety of subcutaneous administration amphetamine or methylphenidate. Although may increase the rate of gastrointestinal and renal impairment (particularly in persons taking concomitant drugs) and potentially lead to hyperkinetic reactions, this risk is considered to be low in otherwise healthy persons and is probably not an important concern when using these drugs in pediatric patients with autism. Drug Interactions Drug interactions have been reported in clinical trials of MPH administration. In general, the following effects have been reported when the drugs have been combined. CYP2D6 Inhibitors. Because of the metabolic byproducts MPH metabolism, concomitant Administration of the CYP2D6 Inhibitors Clozapine or Mellaril may result in a slight increase the plasma concentration of MPH. When Clozapine or Mellaril is coadministered with the oral stimulant stimulants, maximum clinically relevant plasma concentration of MPH is 4.5 to 5 times the maximum achievable plasma concentration (Cmax) (see Pharmacokinetics below). Inhibition of Glucose Metabolism. Because the metabolic byproducts of MPH metabolism, concomitant Administration the CYP2D6 Inhibitors Clozapine or Mellaril may result in a slight decrease the plasma concentration of MPH. When Clozapine or Mellaril is coadministered with the oral stimulant stimulants, plasma concentration of MPH may decrease by approximately 50% to 60% of the Cmax. extent decrease will depend on the degree of inhibition by Clozapine or Mellaril, and will be greater for Clozapine than Mellaril. and Mellaril have been found to limited no inhibition of the metabolism MPH. Metabolic Byproducts of Other Drugs or Medical Conditions. Concomitant Administration of the CYP2D6 Inhibitors Clozapine or Mellaril may result in a slight decrease the plasma concentration of MPH. When Clozapine or Mellaril is coadministered with the oral stimulant stimulants, plasma concentration of MPH may decrease by approximately 50% to 60% of the Cmax. extent decrease will depend on the degree of inhibition by Clozapine or Mellaril, and will be greater for Clozapine than Mellaril. and Mellaril have been found to limited no inhibition of the metabolism MPH. Risks Associated with Subcutaneous Administration of Stimulants The most common serious adverse reactions associated with subcutaneous administration of stimulants are gastrointestinal upset and vomiting. If any of the following adverse reactions occur, discontinue the drug and inform prescribing physician immediately: Anorexia Anorexia and weight loss Loss of appetite Incorporation of amphetamine salts (or metabolites) into the body has been associated with hyperthermia and can result in electrolyte imbalance, disturbances, hyperkalemia, and cardiac arrhythmias, as well death. If any of these adverse reactions occur, discontinue the drug and inform prescribing physician immediately: Hyperthermia Pelvic edema Increased blood pressure

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